![]() This research is part of the PhD project of ir. Electrospinning for tissue engineering applications - ScienceDirect Progress in Materials Science Volume 117, April 2021, 100721 Electrospinning for tissue engineering applications Maryam Rahmati a, David K. On top of that, a lot of attention is given to the mechanical properties of the conduit and its individual components, as the mechanical integrity of the conduit is very important. Electrospun nanofiber mats efficiently mimic the extracellular matrix, which makes them ideal tissue engineering. Research on this topic at CTSE is focused on the understanding of the yarn electrospinning process and the optimization of the novel nerve guidance conduit design by tuning the morphology of the different components of the conduit and by adding biological active cues. Electrospinning enables the use of a diverse range of polymers as nonwoven mats. For this novel nerve guidance conduit design, several biocompatible poly(ε-caprolactone) nanoyarns are bundled by electrospinning a poly(ε-caprolactone) nanofibrous shell around the bundle. These conduits, which are placed between the ends of a damaged nerve, have the purpose to guide regenerating neurons in order to reconnect the nerve ends and thereby restore the nerve’s motor and sensory functions. ![]() As example, an innovative design for a nerve guidance conduit can be produced with the yarn electrospinning technique. Nanoyarns, however, could be the next step in the development of advanced substrate designs. Indeed, nanofibers have already proven to have a lot of potential as substrates for nerve regeneration and tendon tissue engineering. Electrospinning and Tissue Engineering Geoffrey R. Although all that is needed in addition to the traditional electrospinning setup is a rotating cone collector and a yarn take-up unit, this new technique significantly expands the number of potential end-products for nanofibers.Īn important potential use of these innovative nanoyarns is tissue engineering scaffolds. However, the recently developed yarn electrospinning technique allows the production of nanofibrous yarns. The typical products used for these applications are nonwovens. Nanofibers have already proven to have a lot of potential as sensors, wound dressings, water treatment membranes etc. This gap can now be filled as recently the yarn electrospinning process was discovered, allowing to electrospin nanofibers in the form of yarns, opening doors towards a whole new world of end-product possibilities, such as nerve regeneration conduits and tendon tissue engineering doi: 10.1177/1528083707078133.Solvent electrospinning has been known for several decades now, yet the typical products that are being produced are nonwovens, thereby ignoring an entire range of potential textile products: yarns and wovens. Electrospun porous mats for high efficiency filtration. doi: 10.4028/ -ĭotti F., Varesano A., Montarsolo A., Aluigi A., Tonin C., Mazzuchetti G. ![]() Design and Manufacture of Nanofibers Using Electrospinning Technique for Aerospace Application. Nisha M., Singh D., Freesta Shiny J., Sasirekha B. Electrospinning-based (bio) sensors for food and agricultural applications: A review. To date, the number of polymers that have been electrospun has exceeded 200. Mercante L.A., Scagion V.P., Migliorini F.L., Mattoso L.H., Correa D.S. Electrospinning is a simple and versatile technique to fabricate continuous fibers with diameter ranging from micrometers to a few nanometers. ![]() The history of the science and technology of electrospinning from 1600 to 1995. Tucker N., Stanger J.J., Staiger M.P., Razzaq H., Hofman K. El electrospinning (hilado electrosttico de fibras) es un. Perspectives and challenges in tissue engineering and regenerative medicine. Key words: Electrospinning Scaffolds Nanofiber Tissue engineering (source: MeSH NLM). ![]()
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